User:     Password:    
Forgotten Password?
SysBio2014 Logo Banner
Nav_arrow Home
Nav_arrow General Information
Nav_arrow Grants & Fellowships
Nav_arrow Scientific Programme
Nav_arrow BB & CP Info
Nav_arrow Social Programme
Nav_arrow Registration
Nav_arrow User Profile Access only for registered users
Nav_arrow Housing & Travel
Nav_arrow Contact
go to
go to BMBF
go to ERASysAPP
go to Systems Biology Researcher Database

Scientific Programme

Detailed Scientific Programme

Plenary Symposia will each be introduced and moderated by the indicated chair person. Lecturers will then discuss their methodologies, discuss these in detail with the students and then show their most recent Systems Biology discoveries.

Download the Scientific Program here

Last Update: Feb 268, 2014 (Speaker Matthias Heinemann replacing Luis Serrano)

Sunday, March 2, 2014
Pre Course Teaching (optional, all day) Download Program & Abstracts here, Software here
PC-01 David Fell Mathematical biochemistry in a nutshell
PC-02 Marcel Schilling Computing in a nutshell
PC-03 Ursula Klingmüller Cell biology in a nutshell
PC-04 Karl Kuchler Molecular genetics in a nutshell
Opening Keynote Lecture (evening)
Uwe Sauer & Karl Kuchler Chairs
Nadja Rosenthal (UK, AUS) Systems approaches to regenerative medicine
Monday, March 3, 2014

Cellular decision making
Frank Bruggeman Chair
Steven Altschuler (US) Using computer vision to identify functional heterogeneity in cellular populations
Ruedi Aebersold (CH) Proteomic data for systems biology
Matthias Heinemann (NL) How do cells adapt to nutrient changes? NEW!!
Tuesday, March 4, 2014

Network biology
Matthias Heinemann Chair
Dana Pe’er (US) Inferring Networks from multidimensional single cell data
Nathan Price (US) Integrative modeling of metabolic and regulatory networks
Terry Hwa (US) On growth laws, catabolite repression, and metabolic coordination
Wednesday, March 5, 2014

Medical systems biology
Edda Klipp Chair
Lucas Pelkmans (CH) A map of hierarchical functional interactions between signaling and membrane trafficking genes in human cells
Eytan Ruppin (IL) Predicting novel cancer drug targets
Karl Kuchler (AT) Dual-systems biology and network inference to study microbial pathogenesis and host pathogen interplays
Thursday March 6, 2014

From molecules to functional phenotypes
Ursula Kummer Chair
Andrew Millar (UK) Unwinding the circadian clock across multiple scales, from gene circuits to plant
Thomas Höfer (DE) Stem cell fate by numbers: immunity and hematopoiesis
Markus Covert (US) Accelerated discovery via a whole-cell model
Friday, March 7, 2014

Systems biology in practice (industry/medicine)
Bas Teusink Chair
Roel Bovenberg
Metabolic Engineering from an industrial perspective (DSM, NL)
Daniel Kirouac
Using network biology to improve oncology drug development
(Merrimack Pharmaceuticals, US)
Ed Driggers
High-throughput integration of broad metabolomic and transcriptional profiles reveals metabolic patways distinguishing m1 and m2 murine macrophage polarization
(Agios Pharmaceuticals, US)
Lars Küpfer
An introduction to physiology-based pharmacokinetic (PBPK) modeling
(Bayer AG, D)
Academic symposium
Peter Lichter The EURAT project - ethical and legal aspects of whole genome sequencing
Thomas Lemberger Scientific papers as open discovery tools
Closing Lecture
Uwe Sauer & Karl Kuchler Chairs
Hans Westerhoff (NL) Discovering (Systems) Biology

Blackboard Teaching

In Black board teaching sessions teachers carefully selected for this mode will explain in the simplest possible terms and in highly interactive mode, principles and methodologies. Detailed information about the Blackboard Teaching & Computer Practicals can be found under Course Information.

Blackboard Teaching (Monday, Tuesday, Thursday afternoon)
Frank Bruggeman Origins of stochasticity in single cells: theory
Julio Saez Rodriguez Logic models of signalling networks and training to phosphoproteomic data
Matthias Heinemann Experimental tools for single cell analyses
Mike Savageau Genotype to phenotype: Phenotypic deconstruction of complex biological systems
Olaf Wolkenhauer Efficient Communication of Interdisciplinary Research
Edda Klipp Modeling signaling networks
Bas Teusink Genome-scale metabolic models, their construction and analysis

Computer Practicals

Computer practicals will demonstrate modern modeling and data analysis tools hand on. Students are advised to bring their own laptops to the practicals as the organizers do not provide laptops. The software used for the practicals will be made available at the course site. Detailed information about the Blackboard Teaching & Computer Practicals can be found under Course Information.

Computer Practicals (Monday, Tuesday, Thursday afternoon)
Akira Funahashi CellDesigner: A process diagram editor for gene-regulatory and biochemical networks
P. Mendes/S. Sahle/U. Kummer Introduction to modeling (using COPASI)
Jacky Snoep Creating a transparent model workflow in JWS Online
Wolfgang Müller/Olga Krebs Data mangement in practice
Brett Oliver Constraint Based Modelling with FAME

Software for Computer Practicals:

Please make sure that your Laptop fullfills the following requirements for your selected computer practicals and that any required software is installed prior to the practicals:

  • Brett Oliver: only wireless Internet connection required.
  • Jacky Snoep: only wireless Internet connection required.
  • Wolfgang Müller/Olga Krebs: Please download and preinstall Rightfield and OpenRefine
  • Akira Funahashi: Please download and preinstall CellDesigner 4.3
  • P. Mendes/S. Sahle/U. Kummer: Please download and preinstall Copasi (latest stable version)

Precourse Teaching

On Sunday March 2, four optional parallel preparatory courses will be held from morning until evening. These courses are intended to teach the basics to stundents who are not firm in the respective topics.

Registering for one of these courses will require an extra night’s accommodation and meals, which we will book for you and it will require us to charge an extra registration fee (€ 150). Please be aware that the number of places for these preparatory courses are limited and acceptance for these courses will be communicated by the organizers.

Software for Preparatory Courses:

Please make sure that your Laptop fullfills the following requirements for your selected Preparatory Course and that any required software is installed prior to the Preparatory Course:

  • David Fell: Please download and preinstall a function plotting package (such as Gnuplot (free) or Matlab), and a spreadsheet program (Excel or Openoffice or similar)
  • Marcel Shilling: Please download and preinstall Copasi

Oral Presentations

Selected "Short Talks" will be delivered during afternoon sessions by principal investigators, graduate students and postdocs. These presentations will be selected by the Scientific Advisory Board on the basis of submitted abstracts. All selected speakers will be notified by e-mail to submit study material in PDF-format about their talk for the students.

Please deliver your presentation on a USB-Stick at least two hours before your talk is sheduled. We will supply OS X 10.6 and Windows 7 Laptops for your presentations. Available software for presentations includes Adobe Acrobat 10, Keynote 2008 (OS X), Microsoft Powerpoint (Win: 2010, OS X: 2011), OpenOffice 3.2 as well as Quicktime and common audio/video codecs. The preferred presentation type is Powerpoint. For any special requirements please contact the meeting office.

Poster Sessions

The poster session represents a vital part of the SysBio Course. All abstracts not selected for oral presentations will be on display as posters during the entire course to provide ample time for informal discussions among students, participants and lecturers. In small-group sessions lecturers will provoke intensive discussions about the posters and about careers and research plans with the individual students.

Poster size: The maximum allowed size for a poster is 120cm height by 90cm width (=47 x 35 inches). The posters will by attached to the boards via adhesive tape, which will be supplied by the organizer. If you have not been notified about giving an oral presentation, you have been selected for a poster presentation.

Young Investigator Awards

All abstracts with graduate students or postdoctoral fellows as first authors are subject to scientific evaluation by selected members of the SAB. The best abstract in each topic shall receive the "SysBio Young Investigator Award".